A study points to a rise in renal carcinomas in children, known as ‘Wilms Tumour’.
Wilms tumour remains the most common type of renal tumour in children, according to a large, international study. Meanwhile, the proportion of renal carcinomas among kids increased with age, and so did their incidence over time — which the authors think may have something to do with environmental factors.
In their study, researchers looked at more than 16,000 cases of malignant renal tumours collected across data from more than 308 population-based cancer registries on 5 continents. The total included 15,320 renal tumours in children aged 0 to 14 years and 800 renal tumours in teens aged 15 to 19 years. The study looked into the incidence of renal tumours in 15 world regions and across 5 ethnic groups in the US. The researchers also investigated time trends in incidence from 1996 to 2010 and trends during 4 decades (between the 1970s and the 2000s).
The age-standardized incidence rate (ASR) of renal tumours among children aged 0 to 14 years was 8.3 per million (95% CI, 8.1-8.4) and 1.4 per million (95% CI, 1.3-1.5) among adolescents aged 15 to 19. The highest ASRs in children were identified in North America and Europe, ranging between 9.1 (95% CI, 8.4-9.7) and 9.8 per million (95% CI, 9.4-10.2). In the US, the highest ASR was found for Black individuals, at 10.9 per million (95% CI, 10.2-11.6).
Wilms tumour was found to be the most common type of renal tumour in children aged 0 to 14 years, both in all the different world regions and in ethnic groups in the US.
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